中华内分泌代谢杂志2024,Vol.40Issue(1) :68-72.DOI:10.3760/cma.j.cn311282-20220126-00060

肢端肥大症合并妊娠一例并文献复习

Acromegaly with pregnancy: A case report and review of literature

鞠姜华 朱惠娟 王林杰 阳洪波 姚勇 段炼 周丽斌
中华内分泌代谢杂志2024,Vol.40Issue(1) :68-72.DOI:10.3760/cma.j.cn311282-20220126-00060

肢端肥大症合并妊娠一例并文献复习

Acromegaly with pregnancy: A case report and review of literature

鞠姜华 1朱惠娟 2王林杰 2阳洪波 2姚勇 3段炼 2周丽斌
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作者信息

  • 1. 中国医学科学院,北京协和医学院,北京协和医院内分泌科,国家卫生健康委员会内分泌重点实验室 100730;鞠姜华现在山东大学齐鲁医院(青岛)内分泌科 266035
  • 2. 中国医学科学院,北京协和医学院,北京协和医院内分泌科,国家卫生健康委员会内分泌重点实验室 100730
  • 3. 中国医学科学院,北京协和医学院,北京协和医院神经外科 100730
  • 折叠

摘要

本文报道1例肢端肥大症患者妊娠期服用溴隐亭并成功分娩的诊治经过。回顾性总结了该患者2次妊娠前后的临床资料及治疗结局。该患者第2次妊娠期间口服溴隐亭,妊娠期病情较稳定,并足月剖宫产1女婴。本文提示肢端肥大症患者在病情稳定后妊娠可获得良好结局,妊娠期服用多巴胺受体激动剂没有增加围产期不良事件。 This article reports the diagnosis and treatment of a case of acromegaly in a pregnant patient who took bromocriptine during pregnancy and delivered successfully. A retrospective summary of the clinical data and treatment outcomes before and after two pregnancies of the patient is provided. The patient took bromocriptine during the second pregnancy, and her condition remained stable. A baby girl was delivered by caesarean section at full term. The article suggests that pregnancy in acromegaly patients, after the stabilization of the condition, can lead to favorable outcomes. The use of dopamine receptor agonists during pregnancy does not increase adverse events during the perinatal period.

Abstract

This article reports the diagnosis and treatment of a case of acromegaly in a pregnant patient who took bromocriptine during pregnancy and delivered successfully. A retrospective summary of the clinical data and treatment outcomes before and after two pregnancies of the patient is provided. The patient took bromocriptine during the second pregnancy, and her condition remained stable. A baby girl was delivered by caesarean section at full term. The article suggests that pregnancy in acromegaly patients, after the stabilization of the condition, can lead to favorable outcomes. The use of dopamine receptor agonists during pregnancy does not increase adverse events during the perinatal period.

关键词

肢端肥大症/妊娠/多巴胺受体激动剂/安全性

Key words

Acromegaly/Pregnancy/Dopamine receptor agonist/Security

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基金项目

中央高水平医院临床科研业务费资助项目(2022-PUMCH-A-155)

中央高水平医院临床科研业务费资助项目(2022-PUMCH-B-016)

出版年

2024
中华内分泌代谢杂志
中华医学会

中华内分泌代谢杂志

CSTPCD北大核心
影响因子:1.747
ISSN:1000-6699
参考文献量23
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