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坏死精子症诊疗进展

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坏死精子症是弱精子症的一类特殊类型,其精子通常大量死亡,发病率为0.2%~0.4%.有关坏死精子症的报道尚十分稀少,其病因冗杂,诊断与治疗也相当棘手.本文将综述坏死精子症的主要病因、病理生理机制、诊断方法及治疗策略,以期能为男科医师及辅助生殖医师提供参考,为坏死精子症患者行辅助生殖技术治疗提供理论指导.
Advances in the diagnosis and treatment of necrozoospermia
Necrozoospermia is a special type of asthenospermia,in which mass sperm death is commonly seen,with an inci-dence rate of 0.2%-0.4%.Studies on necrospermia are rarely reported.Its etiology is complicated,and its diagnosis and treatment are very difficult.This article focuses on the main etiological factors,pathophysiological mechanism,diagnostic methods and treatment strategies of necrospermia,aiming to provide some reference for andrologists and reproduction physicians,as well as a theoretical guid-ance for intracytoplasmic sperm injection(ICSI)in the treatment of the patients with necrospermia.

necrozoospermiasperm DNA fragmentationmale infertilityintracytoplasmic sperm injection

欧阳缔、杨镒魟

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四川大学华西第二医院妇产科生殖医学科/出生缺陷与相关妇儿疾病教育部重点实验室,四川成都 610041

四川大学华西临床医学院,四川成都 610041

坏死精子症 精子DNA碎片 男性不育 卵细胞胞质内单精子注射

国家卫生健康委男性生殖健康重点实验室开放课题

2023GJP01

2024

中华男科学杂志
南京军区南京总医院

中华男科学杂志

CSTPCD
影响因子:1.052
ISSN:1009-3591
年,卷(期):2024.30(3)