Changes in seminal plasma composition and corresponding sperm quality in patients with chronic prostatitis/chronic pelvic pain syndrome:Progress in studies
Prostatitis is one of the three most common prostate diseases in men,the other two being prostatic hyperplasia and prostate cancer,and about 50% of men worldwide have been attacked by prostatitis during their lives.The incidence of infertility is significantly higher in patients with chronic prostatitis/chronic pelvic pain syndrome(CP/CPPS)than in those without it,which is mainly attributed to the changed semen composition of the CP/CPPS patients.Using the key words chronic prostatitis,chronic pelvic pain syndrome,sperm,semen,and seminal plasma,we searched PubMed and Medical Lines online for originals,review articles,clin-ical trials,case reports and associated citations on humans and animals published up to 2024.We comprehensively reviewed the previ-ous studies and investigations relating chronic prostatitis,seminal plasma change and sperm quality,and discussed the impact of the change of semen composition on sperm quality.