Objective:To compare the effect of holmium laser enucleation of the prostate(HoLEP)with that of transurethral resection of the prostate(TURP)on the prostate function,oxidative stress indicators and sexual function of the patient with BPH.Methods:We randomly assigned 100 BPH patients to receive HoLEP(n=50)or TURP(n=50)in our hospital from June 2021 to June 2023,and compared the perioperative parameters,prostate function,oxidative stress indicators,sexual function and postopera-tive complications between the two groups.Results:The intraoperative blood loss was significantly less and the time of catheterization,bladder irrigation and hospital stay remarkably shorter in the HoLEP than in the TURP group(P<0.05).The postoperative IPSS and quality of life(QOL)scores were markedly lower,level of superoxide dismutase(SOD)higher,content of malondialdehyde(MDA)and total antioxidant capacity(T-AOC)lower,IIEF-5 and Erection Hardness Grading Scale(EHGS)scores higher,and incidence of postoperative complications lower in the HoLEP than in the TURP group(all P<0.05).Conclusion:HoLEP is superior to TURP in improving the prostate function,oxidative stress indicators and sexual function of the patient with BPH.
关键词
经尿道前列腺钬激光剜除术/经尿道前列腺电切术/良性前列腺增生/前列腺功能
Key words
holmium laser enucleation of the prostate/transurethral resection of the prostate/benign prostatic hyperplasia/prostate function