中华男科学杂志2024,Vol.30Issue(8) :717-721.DOI:10.13263/j.cnki.nja.2024.08.007

经尿道前列腺钬激光剜除术与经尿道前列腺电切术对良性前列腺增生患者前列腺功能、氧化应激指标及性功能的影响比较

HoLEP versus TURP in improving the prostate function,oxidative stress indicators and sexual function of the patient with BPH

魏小辉 顾奕波
中华男科学杂志2024,Vol.30Issue(8) :717-721.DOI:10.13263/j.cnki.nja.2024.08.007

经尿道前列腺钬激光剜除术与经尿道前列腺电切术对良性前列腺增生患者前列腺功能、氧化应激指标及性功能的影响比较

HoLEP versus TURP in improving the prostate function,oxidative stress indicators and sexual function of the patient with BPH

魏小辉 1顾奕波2
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作者信息

  • 1. 常州市妇幼保健院泌尿外科,江苏常州 213000
  • 2. 常州市第一人民医院手术室,江苏常州 213000
  • 折叠

摘要

目的:比较经尿道前列腺钬激光剜除术(HoLEP)与经尿道前列腺电切术(TURP)对良性前列腺增生患者前列腺功能、氧化应激指标及性功能的影响.方法:选取2021年6月至2023年6月我院接收的100例良性前列腺增生患者,按信封抽签法随机分为TURP组(n=50)和HoLEP组(n=50).TURP组经TURP治疗,HoLEP组经HoLEP治疗.比较两组的围术期指标,治疗前后前列腺功能、氧化应激指标、性功能及并发症.结果:Ho-LEP组的术中出血量、尿管留置时间、膀胱冲洗时间、住院时间均低于TURP组(P<0.05).术后,HoLEP组国际前列腺症状(IPSS)评分、生活质量(QOL)评分低于TURP组(P<0.05);HoLEP组的超氧化物歧化酶(SOD)水平高于TURP组,丙二醛(MDA)和总抗氧化能力(T-AOC)低于TURP组(P<0.05);HoLEP组国际勃起功能指数(IIEF-5)评分、勃起硬度分级量表(EHGs)评分高于TURP组(P<0.05).HoLEP组的并发症发生率低于TURP组(P<0.05).结论:HoLEP较TURP对良性前列腺增生患者前列腺功能、氧化应激指标及性功能的影响更为良好.

Abstract

Objective:To compare the effect of holmium laser enucleation of the prostate(HoLEP)with that of transurethral resection of the prostate(TURP)on the prostate function,oxidative stress indicators and sexual function of the patient with BPH.Methods:We randomly assigned 100 BPH patients to receive HoLEP(n=50)or TURP(n=50)in our hospital from June 2021 to June 2023,and compared the perioperative parameters,prostate function,oxidative stress indicators,sexual function and postopera-tive complications between the two groups.Results:The intraoperative blood loss was significantly less and the time of catheterization,bladder irrigation and hospital stay remarkably shorter in the HoLEP than in the TURP group(P<0.05).The postoperative IPSS and quality of life(QOL)scores were markedly lower,level of superoxide dismutase(SOD)higher,content of malondialdehyde(MDA)and total antioxidant capacity(T-AOC)lower,IIEF-5 and Erection Hardness Grading Scale(EHGS)scores higher,and incidence of postoperative complications lower in the HoLEP than in the TURP group(all P<0.05).Conclusion:HoLEP is superior to TURP in improving the prostate function,oxidative stress indicators and sexual function of the patient with BPH.

关键词

经尿道前列腺钬激光剜除术/经尿道前列腺电切术/良性前列腺增生/前列腺功能

Key words

holmium laser enucleation of the prostate/transurethral resection of the prostate/benign prostatic hyperplasia/prostate function

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基金项目

江苏省自然科学基金青年基金(SBK202004300)

出版年

2024
中华男科学杂志
南京军区南京总医院

中华男科学杂志

CSTPCD
影响因子:1.052
ISSN:1009-3591
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