Mitochondrial damage and male reproductive dysfunction:Progress in research
Mitochondria are the center of sperm metabolism and essential for all aspects of flagellar motility,capacitation,acro-some reaction and gametic fusion of sperm.Abnormalities in the mitochondrial ultrastructure,membrane potential,reactive oxygen spe-cies,Ca2+homoeostasis,sperm apoptosis,mitochondrial DNA,mitochondrial enzymes and proteomic activity can decrease sperm quality and even cause male infertility.This paper elucidates the impact of mitochondrial dysfunction on sperm by reviewing and analy-zing relevant literature on mitochondria and male reproductive function,aiming to provide some theoretical evidence for exploring effec-tive interventions for male reproductive dysfunction.
万方数据
维普
