This paper uses the method of intermediary variables to explore the mechanism of the development of rural e-commerce in alleviating multi-dimensional relative poverty in rural areas.The research shows that the poverty reduction effect of rural e-commerce on rural poor people is gradually enhanced from the eastern part of our country to the western region,the effect of engaging in agricultural production is stronger than that of non-agricultural production,and most of the people with higher education background are poor people.The effect of getting rid of poverty is more obvious.Rural e-commerce can alleviate poverty by promoting entrepreneurship among the poor.