Deepening the integration of industry and education and cultivating top-notch and innovative talents in the agricultural industry is the key to the revitalization of rural talents and the construction of a powerful agricultural country.Based on the contradictions and challenges existing in the cultivation of top-notch innovative talents in agricultural colleges and universities,such as the contradictions between new and old,more and less,fast and slow,this paper focuses on the era and mission of the integration of agricultural industry chain and education chain.This paper puts forward a new talent training path of"one carrier,two teams,triple-helix,four-wheel drive and five forces".The paper also introduces the innovative entrepreneurship education and teaching system of Guangxi Vocational University of Agriculture,i.e.,"one body,two wings,four completions,four changes,and five fields of talents",in order to strengthen the cultivation of top-notch innovative talents in agriculture and promote agricultural colleges and universities to achieve innovation and breakthrough in personnel training.