Dynamic adsorption of different resins for four salvianolic acids from Salviae miltiorrhizae Radix et Rhizoma
AIM To study the adsorption properties of the three different resins for the four salvianolic acids (danshensu, protocate chualdehyde, salvianolic acid D and salvianolic acid B) . METHODS Four salvianolic acids were employed as markers to evaluate adsorption leaking curves, dynamic adsorption capacities, desorption curves and desorption ratios on three different resins (macroporous resin, polyamide resin and anion exchange resin). RESULTS AB-8 macroporous resin was a suitable resin to purify salvianolic acid D and salvianolic acid B, and their dynamic adsorption capacities, similar to polyamide resin and much higher than 201 ×7 type anion resin, were 22. 3 mg/g and 27. 4 mg/g, respectively. The dynamic adsorption capacities of danshensu and protocate chualdehyde on anion exchange resin which were 30. 8 mg/g and 3. 2 mg/g, respectively, were greater than those of other two resins. CONCLUSION Combination of macroporous resin with anion exchange resin to separate and purify salvianolic acids is feasible and necessary.
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NSTL
万方数据
维普
