杭白菊木脂素类成分研究
Lignans from Chrysanthemum morifolium
杨鹏飞 1刘华 1张增辉 2孙正光 1黄申 1钱玉梅 3毛多斌1
作者信息
- 1. 郑州轻工业大学烟草科学与工程学院, 河南 郑州 450002
- 2. 陕西中烟工业有限责任公司技术中心,陕西 西安 710000
- 3. 广西中烟工业有限责任公司技术中心, 广西 南宁 530000
- 折叠
摘要
目的 研究杭白菊木脂素类成分.方法 采用大孔吸附树脂、Sephadex LH-20 凝胶柱色谱和制备型HPLC对杭白菊 80%乙醇提取物进行分离纯化,根据理化性质及波谱数据鉴定所得化合物的结构.结果 从中分离得到 11 个化合物,分别鉴定为ssioriside(1)、nudiposide(2)、lyoniside(3)、tortoside A(4),viburfordoside E(5)、tiliamuroside A(6)、开环异落叶松脂素-4-O-β-D-吡喃葡萄糖苷(7)、异落叶松脂醇-4-O-β-D-吡喃葡萄糖苷(8)、异落叶松脂醇-9-O-β-D-吡喃木糖苷(9)、5′-甲氧基-异落叶松脂醇-9′-O-β-D-吡喃木糖苷(10)、(7R,8R)-4,7,9,9′-四羟基-3,3′-二甲氧基-8-O-4′-新木脂素(11).结论 化合物 1～11 均为首次从该植物中得到.
Abstract
AIM To study the chemical constituents of lignans from the flowers of Chrysanthemum morifolium Ramat..METHODS 80%ethanol extraction of C.morifolium flowers was isolated and purified by macroporous adsorption resin,Sephadex LH-20 and preparative HPLC,and structures of all obtained compounds were determined by their spectral data and physicochemical properties.RESULTS Eleven lignans were isolated and identified as ssioriside(1)、nudiposide(2)、lyoniside(3)、tortoside A(4),viburfordoside E(5)、tiliamuroside A(6)、secoisolariciresinol 4-O-β-D-glucopyranoside(7)、isolariciresinol 4-O-β-D-glucopyranoside(8)、isolariciresinol 9-O-β-D-xylocopyranoside(9)、5′-methoxy-isolariciresinol 9′-O-β-D-xylopyranoside(10)、(7R,8R)-4,7,9,9′-tertahydroxy-3,3′-dimethoxy-8-O-4′-oxyneolignan(11).CONCLUSION All compounds are obtained from C.morifolium for the first time.
关键词
杭白菊/木脂素/分离鉴定Key words
Chrysanthemum morifolium Ramat./lignans/isolation and identification引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
维普
万方数据