首页|灵仙通络胶囊联合温通针法对腰椎间盘突出症患者的临床疗效

灵仙通络胶囊联合温通针法对腰椎间盘突出症患者的临床疗效

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目的 考察灵仙通络胶囊联合温通针法对腰椎间盘突出症患者的临床疗效.方法 104 例患者随机分为对照组和观察组,每组 52 例,2 组均采用常规治疗,同时对照组给予温通针法,观察组在对照组基础上加用灵仙通络胶囊,疗程 30 d.检测临床疗效、中医证候评分、腰椎功能指标(ODI指数评分、JOA评分)、VAS评分、炎症因子(TNF-α、IL-1β、IL-6)、血液流变学指标(血浆黏度、全血高切黏度、全血低切黏度)、不良反应发生率变化.结果 观察组总有效率高于对照组(P<0.05).治疗后,2 组中医证候评分、ODI指数评分、VAS评分、炎症因子、血液流变学指标降低(P<0.05),JOA评分升高(P<0.05),以观察组更明显(P<0.05).2 组不良反应发生率比较,差异无统计学意义(P>0.05).结论 灵仙通络胶囊联合温通针法可安全有效地缓解腰椎间盘突出症患者临床症状,促进腰椎功能恢复,降低疼痛程度,减轻炎症反应,改善血液流变学.
Clinical effects of Lingxian Tongluo Capsules combined with Wentong Acupuncture Method on patients with lumbar disc herniation
AIM To investigate the clinical effects of Lingxian Tongluo Capsules combined with Wentong Acupuncture Method on patients with lumbar disc herniation.METHODS One hundred and four patients were randomly assigned into control group(52 cases)for 30-day intervention of both Wentong Acupuncture Method and conventional treatment,and observation group(52 cases)for 30-day intervention of Lingxian Tongluo Capsules,Wentong Acupuncture Method and conventional treatment.The changes in clinical effects,TCM syndrome scores,lumbar function indices(ODI index score,JOA score),VAS score,inflammatory factors(TNF-α,IL-1β,IL-6),hemorheological indices(plasma viscosity,whole blood high-shear viscosity,whole blood low-shear viscosity)and incidence of adverse reactions were detected.RESULTS The observation group demonstrated higher total effective rate than the control group(P<0.05).After the treatment,the two groups displayed decreased TCM syndrome scores,ODI index score,VAS score,inflammatory factors and hemorheological indices(P<0.05),and increased JOA score(P<0.05),especially for the observation group(P<0.05).No significant difference in incidence of adverse reactions was found between the two groups(P>0.05).CONCLUSION For the patients with lumbar disc herniation,Lingxian Tongluo Capsules combined with Wentong Acupuncture Method can safely and effectively relieve clinical symptoms,promote lumbar function recovery,reduce pain degree,alleviate inflammatory responses,and improve hemorheology.

Lingxian Tongluo CapsulesWentong Acupuncture Methodconventional treatmentlumbar disc herniation

徐力、李永琳、韩聪、张英、涂婷、高源、李群、刘庆

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西南医科大学附属中医医院疼痛科,四川 泸州 646000

西南医科大学附属中医医院内分泌代谢科,四川 泸州 646000

灵仙通络胶囊 温通针法 常规治疗 腰椎间盘突出症

四川省科技计划

2021YJ0181

2024

中成药
国家食品药品监督管理局,信息中心中成药信息站,上海中药行业协会

中成药

CSTPCD北大核心
影响因子:1.217
ISSN:1001-1528
年,卷(期):2024.46(5)
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