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白及饮片等级评价

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目的 评价白及饮片等级.方法 测定正品形态参数及白及苷、白及多糖含量,计算质量常数相关数值,进行等级划分.电子眼测定饮片颜色,Pearson相关性分析探讨颜色与等级之间的关联.以ADP为诱导剂,比浊法比较不同等级饮片对家兔血小板聚集的作用.结果 29批正品划分为3个等级,其中一等品3批[相对质量常数(A')≥68.99],二等品9批(43.12≤A'<68.99),三等品17批(A'<43.12).颜色与等级呈显著相关性.各等级饮片均能促进血小板聚集,而且作用随等级升高而增强.结论 本研究首次制定了白及饮片等级标准,证明了其优质优效,可为其等级应用、质量控制提供依据.
Grade evaluation of Bletillae Rhizoma decoction piece
AIM To evaluate the grade of Bletillae Rhizoma decoction piece.METHODS The morphological parameters and militarine,polysaccharide contents for authentic product were determined,after which relevant values of quality constants were calculated,gradation was performed.Electronic eye was adopted in the determination of decoction piece color,after which Pearson correlation analysis was applied to exploring the correlation between color and grade.With ADP as an inducer,the effects of different grades of decoction pieces on rabbit platelet aggregation were compared by turbidimetric method.RESULTS Twenty-nine batches of authentic products were divided into three grades,3 of which were the first-grade products[relative quality constant (A') was≥68.99],9 of which were the second-grade products (43.12≤A'<68.99),17 of which were the third-grade products (A'<43.12).A significant correlation was observable between color and grade.Various grades of decoction pieces could promote platelet aggregation,and the effect was enhanced with the increase of grade.CONCLUSION This study establishes the grade standard for Bletilla Rhizoma decoction piece for the first time,along with the improvement of high quality and excellent effect,which can provide basis for its grade application and quality control.

Bletilla Rhizoma decoction piecegradequality constantscolorplatelet aggregation

陈芳芳、章军、邸继鹏、赵桉熠、许煜迪、陈畅、刘安、郭丛、闫智勇

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西南交通大学生命科学与工程学院,四川 成都 610031

中国中医科学院中药研究所,北京100700

白及饮片 等级 质量常数 颜色 血小板聚集

2024

中成药
国家食品药品监督管理局,信息中心中成药信息站,上海中药行业协会

中成药

CSTPCD北大核心
影响因子:1.217
ISSN:1001-1528
年,卷(期):2024.46(12)