中成药2024,Vol.46Issue(12) :3917-3925.DOI:10.3969/j.issn.1001-1528.2024.12.004

白及饮片等级评价

Grade evaluation of Bletillae Rhizoma decoction piece

陈芳芳 章军 邸继鹏 赵桉熠 许煜迪 陈畅 刘安 郭丛 闫智勇
中成药2024,Vol.46Issue(12) :3917-3925.DOI:10.3969/j.issn.1001-1528.2024.12.004

白及饮片等级评价

Grade evaluation of Bletillae Rhizoma decoction piece

陈芳芳 1章军 2邸继鹏 2赵桉熠 2许煜迪 2陈畅 2刘安 2郭丛 2闫智勇3
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作者信息

  • 1. 西南交通大学生命科学与工程学院,四川 成都 610031;中国中医科学院中药研究所,北京100700
  • 2. 中国中医科学院中药研究所,北京100700
  • 3. 西南交通大学生命科学与工程学院,四川 成都 610031
  • 折叠

摘要

目的 评价白及饮片等级.方法 测定正品形态参数及白及苷、白及多糖含量,计算质量常数相关数值,进行等级划分.电子眼测定饮片颜色,Pearson相关性分析探讨颜色与等级之间的关联.以ADP为诱导剂,比浊法比较不同等级饮片对家兔血小板聚集的作用.结果 29批正品划分为3个等级,其中一等品3批[相对质量常数(A')≥68.99],二等品9批(43.12≤A'<68.99),三等品17批(A'<43.12).颜色与等级呈显著相关性.各等级饮片均能促进血小板聚集,而且作用随等级升高而增强.结论 本研究首次制定了白及饮片等级标准,证明了其优质优效,可为其等级应用、质量控制提供依据.

Abstract

AIM To evaluate the grade of Bletillae Rhizoma decoction piece.METHODS The morphological parameters and militarine,polysaccharide contents for authentic product were determined,after which relevant values of quality constants were calculated,gradation was performed.Electronic eye was adopted in the determination of decoction piece color,after which Pearson correlation analysis was applied to exploring the correlation between color and grade.With ADP as an inducer,the effects of different grades of decoction pieces on rabbit platelet aggregation were compared by turbidimetric method.RESULTS Twenty-nine batches of authentic products were divided into three grades,3 of which were the first-grade products[relative quality constant (A') was≥68.99],9 of which were the second-grade products (43.12≤A'<68.99),17 of which were the third-grade products (A'<43.12).A significant correlation was observable between color and grade.Various grades of decoction pieces could promote platelet aggregation,and the effect was enhanced with the increase of grade.CONCLUSION This study establishes the grade standard for Bletilla Rhizoma decoction piece for the first time,along with the improvement of high quality and excellent effect,which can provide basis for its grade application and quality control.

关键词

白及饮片/等级/质量常数/颜色/血小板聚集

Key words

Bletilla Rhizoma decoction piece/grade/quality constants/color/platelet aggregation

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出版年

2024
中成药
国家食品药品监督管理局,信息中心中成药信息站,上海中药行业协会

中成药

CSTPCDCSCD北大核心
影响因子:1.217
ISSN:1001-1528
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