首页|内蒙古地区牛羊口蹄疫灭活疫苗的免疫效果比较研究

内蒙古地区牛羊口蹄疫灭活疫苗的免疫效果比较研究

扫码查看
为准确掌握牛羊口蹄疫疫苗免疫效果,2012年对内蒙古自治区的牛羊口蹄疫O-Asia I型双价灭活疫苗和牛羊口蹄疫A型灭活疫苗免疫效果进行了监测.采用液相阻断ELISA方法,共检测了8个旗县23018份免疫牛羊口蹄疫O-Asia I型双价灭活疫苗和牛羊口蹄疫A型灭活疫苗15日、30日、60日的血清中口蹄疫免疫抗体水平.结果显示,牛羊口蹄疫疫苗免疫效果总体良好,免疫抗体合格率超过了70%.规模化奶牛养殖场免疫效果稳定,散养地区免疫效果稳定性差,且不同厂家的疫苗免疫效果不同,加强免疫后A、B、D三个厂家抗体合格率能达到100%,C厂家的免疫效果较差,抗体合格率为93.3%.采用3ABC-ELISA检测试剂盒对部分地区牛羊进行感染抗体检测,结果为阴性.
The Research on Comparison of Inactivated Vaccine between Cattle and Sheep with Foot and Mouth Disease in Inner Mongolia
In order to master the immune effect of foot and mouth disease ( FMD) vaccine accurately, we monitored the immunity efficacy of foot and mouth disease vaccines used in Inner Mongolia in 2012. We collected 23018 serums of animals from 8 flag counties which had been immunized with strain 0 and strain Asia I foot and mouth disease inactivated bivalent vaccine 15 days, 30 days, 60 days ago. The antibody titer was detected by liquid phase blocking ELISA. The results showed that the overall immunity efficacy of foot and mouth disease vaccine was good, and the qualified rate of immune antibody was 70%;the immunity efficacy of large-scale farmers was steady, and it showed poor stability in free-ranging areas. The immunity efficacy of foot and mouth disease vaccines from different manufacturers was different. After booster immunization, the immune antibody of the vaccines from manufacturers A, B and D were completely qualified. The vaccines from manufacturer C showed poorer immune effect, the qualified rate was 93.3%. We conducted antibody detection to cattle and sheep from different areas using 3ABC-ELISA detection kit, the results were negative.

foot and mouth diseasetype O-Asiaantibody monitoringimmunization effect

高日明、马立峰、李敏、范秀丽、孙树民、赵心力

展开 >

金宇保灵生物药品有限公司,呼和浩特010030

内蒙古自治区动物疫病预防控制中心,呼和浩特010020

内蒙古民族大学动物科学技术学院,内蒙古通辽028042

口蹄疫 O-Asia I型 监测 免疫效果

内蒙古自治区自然科学基金

2011MS0404

2014

中国兽药杂志
中国兽医药品监察所

中国兽药杂志

CSTPCD北大核心
影响因子:0.49
ISSN:1002-1280
年,卷(期):2014.48(4)
  • 10
  • 2