Clinical Effect of Carprofen Injection in Adjuvant Treatment of Bovine Respiratory Disease
In order to evaluate the clinical efficacy of carprofen injection in the adjuvant treatment of bovine respiratory disease,carprofen injection was divided into three dose groups of low,medium and high(0.7,1.4 and 2.8 mg/kg bw),which were administered subcutaneously to diseased cows suffering from respiratory disease on the basis of the recommended dose(2.5 mg/kg bw)of tulathromycin injection.While carprofen injection from Zoetis UK Limited was administrated at a dose of 1.4 mg/kg bw on the basis of recommended dose(2.5 mg/kg bw)of tulathromycin injection as the control group.The recommended dose(2.5 mg/kg bw)of tulathromycin injection was only injected subcutaneously as a blank control group.The results showed that the combination of carprofen injection and tulathromycin injection for the treatment of bovine respiratory disease could control the symptoms of diseased cows more rapidly and effectively,eliminate the inflammatory response and improve the treatment success rate compared with tulathromycin injection alone.There was no significant difference(P>0.05)in the effect of medium and high doses of carprofen injection,and the effect was comparable(P>0.05)to that of using the recommended dose of carprofen injection produced by Zoetis UK Limited,both of which were significantly better than the low dose of carprofen injection(P<0.05).Carprofen injection at a single dose of 1.4 mg/kg bw subcutaneously,in combination with appropriate antibacterial drugs,had good therapeutic effects on bovine respiratory diseases.