In order to compare the different methods for the determination of baicalin-zinc complex and establish a simpler and faster content determination method,HPLC method and atomic absorption spectrophotometry method were used to study the content determination of baicalin-zinc complex.The linear range of baicalin-zinc complex was 10.0～200.0 μg/mL(r=0.9999),and the precision(RSD=0.08％)was good by HPLC.The linear range of atomic absorption spectrometry was 0～2.0 μg/mL(r=0.9983),and the precision(RSD=0.13％)was good,but the pretreatment process was too complex and time-consuming.The HPLC method was simpler,faster and accurater,which could be used to determine the content of baicalin-zinc complex.
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