Research Progress of Canine Atopic Dermatitis and Its Therapeutic Drugs
Canine atopic dermatitis is an allergic skin disease with a genetic predisposition.Due to the increasing number of dogs in China in recent years,canine atopic dermatitis has become a common disease in pet clinic,which seriously endangers the health of dogs.In addition,the pathogenesis of this disease is complex,which can be roughly summarized into five aspects:genetic factors,environmental factors,skin barrier dysfunction,immune dysfunction and microbial flora dysfunction.Moreover,because its clinical symptoms are similar to other allergic reactions and inflammatory reactions,it is difficult to diagnose,and it needs to be judged by a variety of clinical reactions.In recent years,with the continuous development of the diagnosis and treatment of small animals,the treatment of canine atopic dermatitis has increased the use of anti-inflammatory and anti-itch drugs,JAK pathway inhibitors,biomass drugs and PDE-4 selective inhibitors on the basis of previous basic therapies.In this paper,the etiology,clinical symptoms,diagnosis and treatment methods of canine atopic dermatitis were reviewed for providing reference for the treatment of canine atopic dermatitis in the future.