Study on the Adjuvant Treatment of Bovine Respiratory Diseases by Carprofen Injection
The trial was designed to evaluate the efficacy of carprofen injection combined with telamycin injection in the treatment of bovine respiratory disease(BRD)and to determine the appropriate dose to administer.Six-four cattle with BRD,randomly divided into 2 groups,groups A and B,with 32 cows each,among them,group A was administered subcutaneously telamycin injection(recommended dose 2.5 mg/kg·bw)and carprofen injection(phase II confirmed dose 1.4 mg/kg·bw),group B was administered subcutaneously telamycin injection(recommended dose 2.5 mg/kg·bw).All drugs were given only once in all test cattle.The clinical symptoms of each group were recorded during the trial and scored it;the adjuvant treatment efficacy of carprofen injection on bovine respiratory diseases was evaluated by the detection of inflammatory factors,pathogenic bacteria and specific pathogen antigens/antibodies in each test cattle.The results showed that carprofen injection combined with thalamycin injection to treat BRD could eliminate the inflammatory response from pathogen infection in cattle in a shorter time than thalamycin injection alone;Using thalamycin injection alone or in combination with carprofen injection for BRD,the serum PCT concentration in sick cattle decreased significantly(P<0.05),but the decrease in the two drugs was more significant(P<0.05).The results showed that carprofen injection is clinically recommended in combination with telamycin injection,one dose,1.4 mg/kg·bw,which can effectively assist in the treatment of bovine respiratory diseases.
NETL
NSTL
万方数据
