Study on the Preparation Technology of Jiawei Chulijing Oral Liquid
To establish the preparation process of the traditional Chinese medicine compound oral liquid of Jiawei Chulijing for the treatment of chicken dysentery.Based on single factor experiments,Box-Behnken response surface design method was used to optimize the preparation process conditions of the oral liquid,with water addition ratio,decoction frequency,and decoction time as evaluation factors,and the comprehensive score of the total content of baicalin and forsythoside A and the extract as evaluation indicators.The results showed that the optimal preparation process for Jiawei Chulijing oral liquid was to add 12 times more water,decoct twice,and decoct for 1 hour.Under these conditions,three validation experiments showed that the total content of baicalin and forsythoside A was 5.53 mg·mL-1,the extract was 15.89％,and the comprehensive score was 93.76 points.The optimized process of this method is stable,reliable,scientifically feasible,and can provide reference for the process research and large-scale production of Jiawei Chulijing Oral Liquid.
chicken dysenterytraditional Chinese medicine compound oral liquidresponse surface experimentpreparation process
NETL
NSTL
万方数据
