Effect of Curcuma longa Extracts on Growth,Antioxidant and Immune Functions of Micropterus salmoides
In order to study the effects of Curcuma longa extracts on the growth,antioxidant capacity and immunity of Micropterus salmoides,the experimental groups were fed with diets containing ethanol or water extracts of Curcuma longa at the level of 1％ for 4 weeks.Body weight and antioxidant indexes in the liver were measured weekly,and the gene expression of inflammatory factors and antiviral proteins in the spleen were detected at the end of the experiment.The results showed that dietary supplementation of Curcuma longa extracts had no significant influence on body weight (P>0.05).In the group fed with ethanol extract,the SOD and AKP activities were significantly higher than those in the control group from the third week (P<0.05),and were significantly higher than those in the group fed with water extract at the fourth week (P<0.05).The CAT,T-AOC and ACP activities in the group fed with ethanol extract were significantly higher than those in other groups (P<0.05),while MDA content was significantly lower than that in other groups at the fourth week (P<0.05).In the group fed with water extract,the SOD activity was significantly higher than that in the control group from the third week (P<0.05).The T-AOC and ACP activities in the group fed with water extract were significantly higher than those in the control group (P<0.05),while the MDA content and CAT activity were significantly lower than those in the control group at the fourth week (P<0.05).The gene expression levels of IL-8,IL-10,TNF-α,IFN-γ,Mx-1 and PKR in the two groups fed with Curcuma longa extracts were dramatically higher than those in the control group (P<0.05).The gene expression levels of IL-10,Mx-1,and PKR in the ethanol extract group were significantly higher than those in the water extract group (P<0.05),while the gene expression level of IFN-γin the water extract group was higher than that in the ethanol extract group (P<0.05).These findings indicated that a diet supplemented with Curcuma longa extracts for 4 weeks can markedly enhance the antioxidant capacity and immunity of Micropterus salmoides,with the ethanol extract of Curcuma longa showing better effects.
ethanol extract of Curcuma longawater extract of Curcuma longagrowthantioxidantimmunity
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