首页|基于膜解剖理论的胸、腹腔镜联合食管癌根治术

基于膜解剖理论的胸、腹腔镜联合食管癌根治术

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目的 探讨膜解剖理论应用于胸、腹腔镜联合食管癌根治术的可行性及临床意义。方法 回顾性分析 2018年12 月~2021 年10 月行基于膜解剖理论的胸、腹腔镜联合食管癌根治术142 例资料。将食管系膜、食管癌以及食管系膜内的神经、血管、淋巴系统、脂肪组织、胃上部、胃左系膜、胃左淋巴结作为一个整体切除。术中可见食管周围含疏松结缔组织的间隙为食管筋膜融合间隙。前10 例使用纳米炭示踪标记,显示食管淋巴液引流至胃左淋巴结。结果 142 例手术顺利,手术时间150~230(184。6±21。3)min,术中出血量20~100(46。7±16。8)ml,清扫淋巴结12~41(23。5±7。3)枚,97 例淋巴结阳性;术后胸腔引流时间3~10(7。1±2。5)d,经口进流食时间5~10(7。6±1。7)d,总住院时间9~20(14。0±4。6)d。术后并发症发生率 21。8%(31/142),包括吻合口漏 7 例(4。9%),吻合口狭窄 9 例(6。3%),声音嘶哑 9 例(6。3%),残胃炎 6 例(4。2%)。无术后出血、乳糜漏、感染或术后 30d内死亡。142 例随访 11~35 个月,中位数 26 个月,无复发和死亡。结论食管周围存在构成"信封"的系膜结构,膜解剖理论适用于食管癌的治疗,基于膜解剖理论的食管癌根治术安全、有效、可行。
Application of Thoracoscopy Combined With Laparoscopy for Radical Esophagectomy Based on Membrane Anatomy Theory
Objective To investigate the feasibility and clinical significance of membrane anatomy theory in the application of thoracoscopic and laparoscopic radical esophageal resection.Methods A retrospective analysis was performed on 142 cases of thoracoscopic and laparoscopic radical esophagectomy based on membrane anatomy theory from December 2018 to October 2021.The esophageal mesangium,esophageal cancer,and nerves,blood vessels,lymphatic system,adipose tissue,upper stomach,left mesangium,and left gastric lymph nodes in the esophageal mesangium were removed as a whole.During the surgery,the space containing loose connective tissue around the esophagus was seen to be the esophageal fascial fusion space.The first 10 cases were labeled with nanocarbon tracer markers,showing esophageal lymphatic drainage to the left gastric lymph node.Results All the 142 patients had smooth surgery.The operation time was 150-230 min(mean,184.6±21.3 min),the intraoperative blood loss was 20-100 ml(mean,46.7±16.8 ml),the number of lymph nodes dissected was 12-41(mean,23.5±7.3),and the positive lymph nodes were found in 97 cases.The postoperative chest drainage time was3-10 d(mean,7.1±2.5 d),the postoperative oral intake time was 5-10 d(mean,7.6±1.7 d),and the total hospital stay was 9-20 d(mean,14.0±4.6 d).The total incidence of postoperative complications was 21.8%(31/142),including 7 cases(4.9%)of anastomotic leakage,9 cases(6.3%)of anastomotic stenosis,9 cases(6.3%)of hoarseness,and6 cases(4.2%)of residual gastritis.There was no postoperative bleeding,chyllevial leakage,infection,or death within 30 d after surgery.The follow-ups of the 142 patients lasted for 11-35 months,with a median of 26 months,and there was no recurrence and death.Conclusions There is a mesangial structure that constitutes an"envelope"around the esophagus.The membrane anatomy theory is suitable for the treatment of esophageal cancer,and radical resection of esophageal cancer based on the theory is safe,effective,and feasible.

Esophageal tumorEsophageal mesenteryThoracoscopic surgeryLaparoscopic surgeryMembrane anatomyRadical resection of esophageal cancer

王敬涛、高不郎、王国俊、李瑞欣、张云飞、丁恒轩

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郑州大学第一附属医院胃肠外科,郑州 450022

食管肿瘤 食管系膜 胸腔镜手术 腹腔镜手术 膜解剖 食管癌根治术

河南省科学技术厅2020河南省重点研发与推广专项(科技攻关)研究河南省高等学校重点科研项目计划

20210231011720B320029

2024

中国微创外科杂志
北京大学

中国微创外科杂志

CSTPCD北大核心
影响因子:2.21
ISSN:1009-6604
年,卷(期):2024.24(1)
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