In this paper,2-(acryloyloxy)ethyl 3-oxobutanoate was synthesized by ester addition method u-sing diethylene-ketone and hydroxyethyl acrylate as raw materials.In this paper,the effects of different catalysts(triethylamine,sodium hydroxide,sodium ethanol,and triethanolamine),co-polymerizing agents(hydroqui-none,2,6-di-tert-butyl-p-cresol,phenothiazine,and dibutyl hydroxytoluene),different reactant ratios,and the amounts of catalysts,co-polymerizing agents,and reaction temperatures on the experimental results were investigated by the single-factor optimization method.The final yield was 92.7%as detected by GC.