缺血再灌注损伤对肝细胞癌患者预后的影响及干预措施
Impact of ischemia-reperfusion injury on the prognosis of hepatocellular carcinoma and clinical intervention choices
马铭秀 1徐锋1
作者信息
- 1. 110004 沈阳,中国医科大学附属盛京医院普通外科
- 折叠
摘要
缺血再灌注损伤(IRI)是肝脏外科常常无法回避的问题.除了引起肝功能损伤,IRI是否影响肝细胞癌患者的预后尚存争议.明确不同程度IRI对患者预后的影响以及恰当的防治策略,对选择合适的手术方案与预防手段具有重要意义.本文就肝细胞癌相关的IRI临床研究进展与干预措施展开综述.
Abstract
Ischemia-reperfusion injury(IRI),a common issue in liver surgeries,is often difficult to be avoided.Apart from inducing liver functional impairment,the impact of IRI on the prognosis of patients with hepatocellular carcinoma(HCC)remains a subject of controversy.It is of vital significance to ascertain the effects of varying degrees of IRI in patient prognosis and to establish appropriate prevention and treatment strategies,which play pivotal roles in selecting suitably surgical approaches and preventive measures.This article provides a comprehensive review of the clinical research progress and intervention measures related to IRI in HCC cases.
关键词
再灌注损伤/癌,肝细胞/肝切除术/肝移植Key words
Reperfusion injury/Carcinoma,hepatocellular/Hepatectomy/Liver transplantation引用本文复制引用
基金项目
辽宁省自然科学基金(2020-MS-181)
出版年
2024
NETL
NSTL
万方数据