Hepatocellular carcinoma(HCC)is one of the common malignant tumors in China,which seriously threatens the health.Surgical resection of HCC lesions is one of the main means to achieve long-term survival,but some patients are already at the middle or late stage since the time of initial diagnosis and surgical resection is not feasible.In recent years,interventional therapy has continuously developed and achieved excellent achievements in the field of HCC,and reasonable application can effectively prolong the survival time of patients.This article discusses the clinical research progress and prospects of vascular interventional therapy in the treatment of advanced HCC.