Portal vein thrombosis(PVT)is a complication of cirrhosis,and its incidence rate is positively correlated with the severity of cirrhosis.Some risk factors related to the occurrence and progression of PVT have been identified.Although the negative impact of fully formed PVT on the surgical outcomes of liver transplant recipients is clear,its impact on the progression of cirrhosis is still uncertain.The PVT treatment plan mainly includes anticoagulants and interventional thrombolysis,which requires specific selection based on the characteristics of each patient's thrombus.This article summarizes the current progress in the definition,epidemiology,pathophysiology,grading,risk factors,diagnosis,natural history,clinical outcomes,and treatment of non-tumor PVT in liver cirrhosis.