高分辨MRI测量大脑中动脉狭窄率的准确性评价
Accuracy of high resolution MRI in measurement of vascular stenosis ratio in atherosclerotic middle cerebral artery
王勇胜 1张文杰 2杨明瑞 1殷志杰 1王静 1钟晓飞 1姜兴岳 1沈善昌1
作者信息
- 1. 滨州医学院附属医院放射科 256600
- 2. 滨州医学院临床医学院,烟台264000
- 折叠
摘要
目的 评价3.0T高分辨率磁共振成像(HR-MRI)技术测量动脉粥样硬化所致大脑中动脉(MCA)狭窄的准确性.方法 对滨州医学院附属医院2017年9月至2018年5月40例经数字减影血管造影(DSA)证实的症状性MCA M1段动脉粥样硬化性狭窄患者,行HR-MRI序列(T1加权像、T2加权像、质子密度加权像)扫描,分别用华法林-阿司匹林症状性颅内动脉疾病实验法(WASID法)、面积测算法在HR-MR图像上测量MCA狭窄率(定量测量),并依据狭窄率判定狭窄程度(半定量测量),以DSA为金标准评价两种测量方法的准确性.结果 符合测量要求标准的30例患者的HR-MRI图像均可清晰显示血管壁结构,血管内缘清晰可辨、光滑,表现为偏心性狭窄.DSA、WASID法、面积测算法测得的MCA狭窄率分别为(82±17)％、(70±12)％、(81±16)％,面积测算法测得的MCA狭窄率与DSA比较,差异无统计学意义(P＞0.005),与DSA的相关性较好(r=0.893);面积测算法测得的狭窄程度符合率较高[符合率为90％ (27/30)].结论 HR-MRI技术能够显示管壁情况,面积测算法在测量MCA狭窄方面准确性高.
Abstract
Objective To evaluate the accuracy of measurements of atherosclerotic middle cerebral artery (MCA) stenosis with 3.0 T high-resolution magnetic resonance imaging (HR-MRI).Methods Forty patients with symptomatic atherosclerotic stenosis of middle cerebral artery (MCA) confirmed by digital subtraction angiography (DSA) in the Affiliated Hospital of Binzhou Medical College from September 2017 to May 2018 were enrolled in the study.Patients were scanned by HR-MRI sequence (including T1WI,T2WI,PDWI).The MCA M1 stenosis rate on HR-MR images was assessed by warfarin-aspirin symptomatic intracranial artery disease (WASID) method and area measurement algorithm,respectively,and based on the stenosis rate the degree of stenosis (semi-quantitative measurement) was determined.The accuracy of the two measurement methods was evaluated with DSA results as the gold standard.Results The HR-MRI images showed the structure of the vessel wall clearly in 30 patients meeting the measurement requirements.The inner edge of the vessel was clearly distinguishable and smooth,showing eccentric stenosis.The stenosis rate of MCA measured by DSA,WASID method and area measurement algorithm were (82± 17)％,(70± 12)％,(81 ± 16)％,respectively (P＞0.05).The result of area measurement algorithm was better correlated with DSA (r=0.893);and the coincidence of the stenosis degree rate of two measurement method was 90％(27/30).Conclusion The area measurement algorithm based on the HS-MRI has high accuracy in measuring the degree of MCA stenosis,which is of high clinical application value.
关键词
磁共振成像/大脑中动脉狭窄/动脉粥样硬化Key words
Magnetic resonance imaging/Middle cerebral artery stenosis/Atherosclerosis引用本文复制引用
出版年
2019
NETL
NSTL
维普
万方数据