Clinical characteristics and related factors of cognition disorders in elderly patients with hypertension
Objective To analyze the clinical characteristics and related factors of cognition disorders in elderly hypertensive patients.Methods It was a cross-sectional study.A total of 612 hypertensive patients with the age of(69.06±6.58)years(median 68.00 years)admitted in the Department of Cardiology,General Hospital of Chinese People's Liberation Army from October 2022 to April 2024 were enrolled.The demographic and clinical data were collected,the cognition status was assessed with Mini-Mental State Examination(MMSE)at admission.The related factors of cognition disorders were analyzed with univariate and multivariate logistic regression.Results The results showed that female hypertensive patients and those with older age,lower education,higher fasting blood glucose(FBG)and diabetes mellitus,higher low-density lipoprotein cholesterol(LDL-C)level,higher systolic blood pressure(SBP)and more cardiovascular comorbidities were likely to have cognition disorders(all P＜0.05).Multivariate logistic regression analysis showed that smoking history,elevated SBP,elevated heart rate,elevated FBG,and elevated LDL-C were independent risk factors for cognition disorders in elderly hypertensive patients,while higher education level was an independent protective factor(all P＜0.05).Conclusion Smoking,increased SBP,increased heart rate,increased FBG,increased LDL-C and lower education level are independently associated with cognition disorders in elderly hypertensive patients.
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