Recent advance in multimodal magnetic resonance imaging of the hippocampus and its circuits in cognitive impairment
张春阳 1张晗 1李娟 1何明利 1王志娟
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作者信息
1. 南京医科大学连云港临床医学院神经内科，连云港 222000
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摘要
海马及其环路在人类的学习、记忆和情绪调控中发挥着至关重要的作用。不管是血管性认知障碍（VCI）还是阿尔茨海默病（AD）患者，海马的损害均是其突出的病理学特征。本文围绕近年来反映VCI和AD相关海马及其环路的解剖、血供、结构和功能等方面的多模态MRI技术研究进展进行综述，旨在为VCI和AD的早期识别与鉴别诊断提供帮助。 The hippocampus and its circuits play crucial roles in human learning, memory, and emotional regulation. Whether it is vascular cognitive impairment (VCI) or Alzheimer's disease (AD), damage to the hippocampus is a prominent pathological feature. This review summarizes the recent advance in multimodal magnetic resonance imaging in anatomy, blood supply, structure and function of the hippocampus and the circuits related to VCI and AD in recent years, aiming to provide help in early recognizing and differentially diagnosing VCI and AD.
Abstract
The hippocampus and its circuits play crucial roles in human learning, memory, and emotional regulation. Whether it is vascular cognitive impairment (VCI) or Alzheimer's disease (AD), damage to the hippocampus is a prominent pathological feature. This review summarizes the recent advance in multimodal magnetic resonance imaging in anatomy, blood supply, structure and function of the hippocampus and the circuits related to VCI and AD in recent years, aiming to provide help in early recognizing and differentially diagnosing VCI and AD.
关键词
海马/海马环路/血管性认知障碍/阿尔茨海默病/多模态MRI技术
Key words
Hippocampus/Hippocampal circuit/Vascular cognitive impairment/Alzheimer's disease/Multimodal magnetic resonance imaging
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