中华神经医学杂志2024,Vol.23Issue(1) :89-94.DOI:10.3760/cma.j.cn115354-20231113-00225

胞葬与脑卒中的研究进展

Recent advance in efferocytosis and stroke

蔺晓瑜 杨佳蕾 张玲
中华神经医学杂志2024,Vol.23Issue(1) :89-94.DOI:10.3760/cma.j.cn115354-20231113-00225

胞葬与脑卒中的研究进展

Recent advance in efferocytosis and stroke

蔺晓瑜 1杨佳蕾 1张玲
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作者信息

  • 1. 首都医科大学附属北京天坛医院神经病学中心,国家神经系统疾病临床医学研究中心,北京 100070
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摘要

脑卒中是一种高发病率、高致残率、高复发率的脑血管疾病。近年来研究发现,神经细胞死亡的清除过程,即细胞胞葬,在脑卒中的病理过程中起到关键作用。本文现围绕近年关于胞葬与脑卒中的研究进展进行综述,以期为脑卒中后神经保护与修复提供新思路。 Stroke is a cerebrovascular disease with high incidence, disability rate, and recurrence. Researches in recent years discover that the clearance of dead cells, efferocytosis, plays a vital role in pathological process of stroke. This article reviews the research progress of relation between efferocytosis and stroke, in order to provide a new perspective for neuroprotective therapies after stroke.

Abstract

Stroke is a cerebrovascular disease with high incidence, disability rate, and recurrence. Researches in recent years discover that the clearance of dead cells, efferocytosis, plays a vital role in pathological process of stroke. This article reviews the research progress of relation between efferocytosis and stroke, in order to provide a new perspective for neuroprotective therapies after stroke.

关键词

脑卒中/胞葬/细胞死亡/神经保护

Key words

Stroke/Efferocytosis/Cell death/Neuroprotection

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基金项目

国家自然科学基金面上项目(82171269)

中国科协青年人才托举工程项目(YESS20220126)

出版年

2024
中华神经医学杂志
中华医学会

中华神经医学杂志

CSTPCD北大核心
影响因子:1.521
ISSN:1671-8925
参考文献量50
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