Recent advance in functional near-infrared spectroscopy in post-stroke depression and cognitive impairment
姬忠敏 1李道静 2张爱梅 2刘凯
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作者信息
1. 济宁医学院临床医学院，济宁 272029
2. 济宁医学院附属医院神经内科，济宁 272029
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摘要
近年来，脑卒中后抑郁（PSD）、脑卒中后认知障碍（PSCI）等作为常见的脑卒中后相关非运动症状，逐渐受到学者们的关注。功能性近红外光谱（fNIRS）技术作为一种新兴的非侵入性神经成像技术，现已广泛应用于神经系统疾病的研究，其可以通过监测脑血液循环和氧合信号的变化，评估患者功能状态和康复情况，目前在PSD及PSCI中的应用研究也越来越多。本文主要围绕fNIRS技术在早期识别PSD、PSCI及探索其神经机制、评估治疗效果等方面的应用研究进展，以及fNIRS技术在临床应用中的优缺点和未来研究方向进行综述，以期为脑卒中患者的情感障碍、认知障碍康复研究提供一些参考借鉴。 In recent years, post-stroke depression (PSD) and post-stroke cognitive impairment (PSCI) have gradually attracted the attention of scholars as common stroke-related non-motor symptoms. As an emerging non-invasive neuroimaging tool, functional near-infrared spectroscopy (fNIRS) has been widely used in the study of neurological diseases, which can evaluate the functional status and recovery of these patients by monitoring changes in cerebral blood circulation and oxygenation signals fNIRS is now being increasingly used in PSD and PSCI studies. This review mainly focuses on the research progress of fNIRS in identifying PSD and PSCI, exploring their neural mechanisms, and evaluating treatment effects, as well as advantages, disadvantages and future development prospects of fNIRS in clinical application, so as to provide some references for research on rehabilitation of affective disorders and cognitive disorders in stroke patients.
Abstract
In recent years, post-stroke depression (PSD) and post-stroke cognitive impairment (PSCI) have gradually attracted the attention of scholars as common stroke-related non-motor symptoms. As an emerging non-invasive neuroimaging tool, functional near-infrared spectroscopy (fNIRS) has been widely used in the study of neurological diseases, which can evaluate the functional status and recovery of these patients by monitoring changes in cerebral blood circulation and oxygenation signals fNIRS is now being increasingly used in PSD and PSCI studies. This review mainly focuses on the research progress of fNIRS in identifying PSD and PSCI, exploring their neural mechanisms, and evaluating treatment effects, as well as advantages, disadvantages and future development prospects of fNIRS in clinical application, so as to provide some references for research on rehabilitation of affective disorders and cognitive disorders in stroke patients.
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