Antimicrobial peptides(AMPs)are amphipathic peptides with antibacterial activity existing in organisms.AMPs can promote the healing of diabetic wounds by participating in regulating the inflammatory reaction of wounds,promoting cell proliferation,migration and angiogenesis,and regulating wound tissue remodeling,and has gradually become a promising drug in the field of wound healing.In this article,the antibacterial mechanism of AMPs,the mechanism of promoting diabetic wound healing and the current optimal design of AMPs on wound healing were reviewed and summarized,and the future prospect of developing effective new AMPs was discussed.
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