首页|采用综合消肿疗法联合淋巴管-静脉吻合术治疗继发性淋巴水肿的临床效果

采用综合消肿疗法联合淋巴管-静脉吻合术治疗继发性淋巴水肿的临床效果

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目的 比较综合消肿治疗(CDT)联合淋巴管-静脉吻合术(LVA)与单纯CDT对继发性淋巴水肿的临床疗效.方法 选取2023年3月至7月深圳市大鹏新区南澳人民医院康复科收治的33例继发性下肢淋巴水肿患者.根据是否行LVA分为CDT联合LVA组及CDT组,其中CDT联合LVA组12例,CDT组21例.CDT组采用标准CDT治疗,CDT联合LVA组在CDT的基础上,采用LVA治疗.比较两组治疗前、治疗1个月及随访6个月患肢周径、视觉模拟量表(VAS)评分及生活质量核心问卷量表(QLQ-C30)评分.结果 两组患者治疗1个月患肢周径、VAS评分及QLQ-C30评分均较治疗前显著改善,差异有统计学意义(P<0.05),两种治疗方式均可改善患肢肿胀、疼痛及生活质量.CDT联合LVA组与CDT组比较,患肢踝部[(3.00±1.49)cm vs(1.35±1.08)cm]、髌骨下缘下10 cm[(2.87±1.51)cm vs(1.64±1.25)cm]、膝中[(3.50±2.44)cm vs(1.34±1.27)cm]、髌骨上缘上 10 cm[(3.87±1.94)cm vs(1.67±1.17)cm]周径,VAS 评分[(4(3,5)分 vs 3(2,4)分]及 QLQ-C30 评分[(11.50±4.40)分vs(7.43±2.42)分]治疗前后差值差异均有统计学意义(P<0.05),CDT联合LVA组较CDT组改善更明显.随访6个月,CDT联合LVA组患肢踝部、髌骨下缘下10 cm、膝中、髌骨上缘上10 cm处周径相较于治疗1个月差异无统计学意义(P>0.05),CDT组相较于治疗1个月差异有统计学意义(P<0.05).结论CDT联合LVA能较大程度改善继发性淋巴水肿患者肢体肿胀程度,缓解疼痛,提高生活质量,其效果优于单纯CDT,且短中期疗效较佳.
Clinical efficacy of complex decongestive therapy combined with lymphaticovenular anastomosis in the treatment of secondary lymphedema
Objective To compare the clinical efficacy of complex decongestive therapy(CDT)combined with lymphaticovenular anastomosis(LVA)and CDT alone in the treatment of secondary lymphedema.Methods Thirty-three patients with secondary lower limb lymphedema admitted to the Rehabilitation Department of Shenzhen Dapeng New Area Nan'ao People's Hospital from March 2023 to July 2023 were selected.The patients were divided into CDT combined with LVA group and CDT group according to underwent LVA or not,among which 12 cases were in CDT combined with LVA group and 21 cases were in CDT group.The CDT group were treated with standard CDT,and the CDT combined with LVA group were treated with LVA on the basis of CDT.The circumference of the affected limb,VAS score,and QLQ-C30 score were compared between the two groups before treatment,after 1 month of treatment,and 6-month follow-up.Results The circumference of the affected limb,VAS score,and QLQ-C30 score of both groups improved significantly compared with pre-treatment,and the differences were statistically significant(P<0.05).Both treatment modalities improved the symptoms of swelling,pain,and quality of life.There were statistically significant differences in the change of circumference of the affected limbs at the ankle[(3.00±1.49)cm vs(1.35±1.08)cm],10 cm below the inferior border of the patella[(2.87±1.51)cm vs(1.64±1.25)cm],mid-knee[(3.50±2.44)cm vs(1.34±1.27)cm],10 cm above the superior border of the patella[(3.87±1.94)cm vs(1.67±1.17)cm],VAS scores[(4(3,5)vs 3(2,4)],and QLQ-C30 scores[(11.50±4.40)vs(7.43±2.42)]between the two groups,and the improvement was more pronounced in the CDT combined with LVA group compared with that in the CDT group.At 6-month follow-up,no significant difference was found in the circumference of the affected limb at the ankle,10 cm below the inferior border of the patella,mid-knee,and 10 cm above the superior border of the patella in the CDT combined with LVA group compared with that after 1 month of treatment(P>0.05),and the difference in the CDT group was significant compared with that after 1 month of treatment(P<0.05).Conclusion CDT combined with LVA can improve the degree of swelling,relieve pain,and improve the quality of life of patients with secondary lymphedema to a greater extent,and its effect is better than that of CDT alone,and the short-and medium-term efficacy is better.

Complex decongestive therapyLymphaticovenular anastomosisSecondary lymphedemaLimb circumference

王季、王淑婷、肖聪慧、廖鑫、严鹭慧、徐姗姗、邓呈亮、王玉龙

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518121 深圳市大鹏新区南澳人民医院康复科

563003 遵义医科大学附属医院烧伤整形外科

综合消肿治疗 淋巴管-静脉吻合术 继发性淋巴水肿 肢体周径

深圳市大鹏新区医疗健康集团医疗卫生科研基金

2022JTLCYJ07

2024

中华损伤与修复杂志(电子版)
中华医学会

中华损伤与修复杂志(电子版)

CSTPCD
影响因子:0.936
ISSN:1673-9450
年,卷(期):2024.19(3)