Research progress on the construction and application of disease models of lung injury with organoid-based approach
Lung organoids are tissue analogues with a certain spatial structure formed by adult stem cells or pluripotent stem cells under 3D culture conditions,which can simulate the structure and function of human tissues to a certain extent. At present,lung organoids have been applied in the construction of lung injury disease models,especially in inhalation lung injury and lung injury caused by infectious diseases. This paper reviews the construction and application of organoids in lung injury disease models in recent years,in order to provide inspiration for the construction of more lung injury models.
万方数据
维普
