Low back pain is a common clinical symptom with complex etiology. Intervertebral disc degeneration is considered to be one of the main causes of low back pain,but its mechanism is not well understood. Gut microbiota is an important part of the digestive tract which can affect host health through a range of metabolites and molecules,but whether gut microbiota is involved in disc degeneration has not been elucidated. Based on the summary of relevant literature,the correlation betweenintestinal flora and intervertebral disc degeneration and the mechanism of intestinal flora participating in intervertebral disc degeneration are summarized as follows.
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