首页|肠道菌群与椎间盘退行性变相关性的研究进展

肠道菌群与椎间盘退行性变相关性的研究进展

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腰痛是一种常见的临床症状,其病因较为复杂.椎间盘退行性变是导致腰痛的主要原因之一,但其发病机制尚不明确.肠道菌群是消化道的重要组成部分,可通过一系列代谢物和分子来影响宿主健康,但肠道菌群是否参与椎间盘退行性变尚无定论.本文通过总结相关文献,对肠道菌群与椎间盘退行性变的相关性以及肠道菌群参与椎间盘退行性变的机制进行综述.
Research progress on the correlation between intestinal flora and intervertebral disc degeneration
Low back pain is a common clinical symptom with complex etiology. Intervertebral disc degeneration is considered to be one of the main causes of low back pain,but its mechanism is not well understood. Gut microbiota is an important part of the digestive tract which can affect host health through a range of metabolites and molecules,but whether gut microbiota is involved in disc degeneration has not been elucidated. Based on the summary of relevant literature,the correlation betweenintestinal flora and intervertebral disc degeneration and the mechanism of intestinal flora participating in intervertebral disc degeneration are summarized as follows.

Intestinal floraIntervertebral disc degenerationIntervertebral disc microbiomeAutoimmunityOsteoporosis

戴睿、张亮、陈浏阳、张永博、吴丕根、孙华、杨盛、孟博

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225001 扬州大学附属苏北人民医院骨科

225001扬州,苏北人民医院骨科

225001 大连医科大学扬州临床医学院骨科

225001 扬州,苏北人民医院骨科

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肠道菌群 椎间盘退行性变 椎间盘微生物组 自身免疫 骨质疏松

2024

中华损伤与修复杂志(电子版)
中华医学会

中华损伤与修复杂志(电子版)

CSTPCD
影响因子:0.936
ISSN:1673-9450
年,卷(期):2024.19(6)