Blood biochemical risk factors of partial necrosis of free flaps:multivariate logistic regression analysis
Objective To explore the relationship between blood biochemical indicators and partial necrosis of free flaps,screen for blood biochemical factors that affect partial necrosis of free flaps,and provide effective indicators for improving the survival rate of free flaps.Methods A retrospective survey was conducted and analyzed.From February 2018 to May 2023,60 cases of limb defect wounds were repaired using a free anterolateral femoral flap in the Department of Traumatology and Orthopedics at our hospital.The preoperative PT values,fibrinogen,hemoglobin,triglycerides,low-density lipoprotein,fasting blood glucose,2-hour postprandial blood glucose,albumin,prealbumin,globulin,total protein,and D-dimer detection values were recorded and analyzed.The biochemical factors with statistical significance were screened out and further multivariate logistic regression analysis was conducted.Results The fibrinogen,hemoglobin,low-density lipoprotein,fasting blood glucose,2-hour postprandial blood glucose,albumin,and D-dimer were risk factors for partial necrosis of free flaps(P＜0.05).Through multivariate logistic regression analysis,the fibrinogen,low-density lipoprotein,fasting blood glucose,2-hour postprandial blood glucose,D-dimer were positively correlated with partial necrosis of free flaps.The hemoglobin and albumin were negatively correlated with partial necrosis of free flaps.Conclusion When fibrinogen is high,hemoglobin is low,low-density lipoprotein is high,fasting blood glucose is high,2-hour postprandial blood glucose is high,albumin is low,and D-dimer is high,it is necessary to be alert to the possibility of partial necrosis of free flaps after surgery,and make corresponding adjustments before surgery to avoid the occurrence of partial necrosis of free flaps.
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