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胎儿生长受限宫内脑损伤相关机制研究进展

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胎儿生长受限(fetal growth restriction,FGR)脑损伤的发病机制可能与氧化应激及神经炎症有关,但确切机制尚不清楚.本文主要围绕FGR脑损伤相关的解剖学改变、潜在的病理生理过程以及不同脑细胞类群参与FGR的具体分子机制进行综述.
Recent research advancements in mechanisms underlying intrauterine brain injury in fetuses with fetal growth restriction
The pathogenesis of brain injury in fetal growth restriction(FGR)fetuses is likely associated with oxidative stress and neuroinflammation,although the exact mechanisms are not fully understood.This article mainly reviews the anatomical alterations,potential pathophysiological processes,and the specific molecular mechanisms involving various types of brain cells in FGR.

Fetal growth retardationNeurodevelopmental disordersOligodendrogliaNeurons

张有振、黄娜娜、赵扬玉

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北京大学第三医院妇产科,北京 100191

胎儿生长迟缓 神经发育障碍 少突神经胶质 神经元

国家自然科学基金

81971399

2024

中华围产医学杂志
中华医学会

中华围产医学杂志

CSTPCD北大核心
影响因子:1.438
ISSN:1007-9408
年,卷(期):2024.27(2)
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