Objective To explore the clinical efficacy of the combined posterolateral and medial approaches for the treatment of trimalleolar fractures.Methods A retrospective study was conducted on the clinical data of 60 patients with trimalleolar fractures admitted to Jiangyin Huiyou Orthopaedic Hospital from June 2021 to June 2022.According to the surgical plan,they were divided into a control group and an experimental group,with 30 cases in each group.The control group received traditional lateral approach combined with medial incision treatment,while the experimental group received modified lateral combined with medial incision treatment.Compare the surgical time,the postoperative recovery time(callus formation time,weight-bearing time),and the total incidence of complications(nerve injury,fracture displacement,delayed fracture healing)for one year after surgery between the two groups of patients.Results The operative time in the experimental group were significantly lower than those in the control group(P<0.05);The callus formation and weight-bearing walking time in the experimental group were significantly shorter than those in the control group(P<0.05).One year after surgery,the incidence of complications in the experimental group was lower than that in the control group,but the difference was not statistically significant(P>0.05).Conclusion The combination of posterolateral and medial incision in the treatment of trimalleolar fracture can shorten the operation time,reduce postoperative complications and effectively promoting postoperative healing in patients.