摘要
目的:集束化干预是提高医疗质量和改善患者结局的一种结构化方法。本文旨在探讨咳嗽抑制治疗为主的集束化干预模式在改善肺癌术后顽固性咳嗽（PIC）中的效果。方法:共纳入2020年2月至2021年8月在南京医科大学附属淮安第一医院行胸腔镜下肺癌根治术的肺癌患者222例，其中2021年1月至8月共108例（研究组）围手术期采用咳嗽抑制训练为主的集束化干预；2020年2月至12月共114例患者（对照组）按常规处理。统计两组患者术后3个月咳嗽症状的变化差异以及不同阶段PIC的发生率。结果:单因素重复测量方差分析结果表明研究组患者与对照组患者术后咳嗽症状评分随治疗时间变化趋势不同（F＝5.288，P<0.05）；两组患者在术后1个月和术后3个月时咳嗽程度上存在明显差异（χ2＝8.755、8.208，P<0.05）；研究组术后2周、术后1个月、术后3个月PIC的发生率（χ2＝5.299、6.361、4.808，P<0.05）均明显低于对照组。结论:采取以咳嗽抑制治疗为主的集束化干预措施可以有效改善肺癌患者术后PIC、提高患者生活质量。
Abstract
Objective:Cluster intervention is a structured approach to improving medical quality and improving patient outcomes. This article aims to explore the role of cluster intervention primarily focused on cough suppression therapy in postoperative intractable cough (PIC) of lung cancer patients.Methods:A total of 222 patients with right lung cancer who underwent thoracoscopic radical resection of lung cancer in The Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University from February 2020 to August 2021 were included in this study. A total of 108 patients (study group) adopted the concept of cluster intervention, mainly focused on cough suppression therapy during the perioperative period. From February to December 2020, 114 patients (control group) were treated as routine. The differences in cough symptoms and the incidence of PIC at different stages between the two groups in 3 months after surgery were statistically analyzed.Results:The results of one-way repeated measurement variance analysis showed that the postoperative cough symptom scores of patients between the two groups showed different trends with treatment time (F=5.288, P<0.05) . There is a significant difference in cough severity between the two groups of patients in 1 month and 3 months after surgery (χ2=8.755, 8.208, P<0.05) . The incidence of PIC (χ2=5.299, 6.361, 4.808, P<0.05) in the study group was significantly lower than those in the control group at 2 weeks, 1 month and 3 months after the operation.Conclusions:Adopting cluster intervention measures mainly focused on cough suppression therapy can effectively improve PIC in lung cancer patients and improve their quality of life.
万方数据