Revascularization strategies and clinical controversies in chronic limb-threatening ischemia
刘昌伟 1汪鹏 1王丽萍
扫码查看
点击上方二维码区域,可以放大扫码查看
作者信息
1. 中国医学科学院 北京协和医学院 北京协和医院血管外科,北京 100730
折叠
摘要
慢性肢体威胁性缺血(CLTI)的发病率随着人口老龄化的加剧逐年升高,患者的生活质量和预期寿命也受到严重影响。有效的血运重建是CLTI患者缓解症状和恢复创面的重要治疗手段,但病变血管的术后管腔再狭窄率仍较高,且再次手术的疗效也不尽如人意。因此,CLTI的首次治疗策略对其预后尤为重要,但目前对于CLTI的治疗策略仍有争议,尤其是在干预时机、干预策略以及干预手段等方面。本文就目前CLTI的血运重建策略及其临床争议性问题进行简要阐述。 The prevalence of chronic limb-threatening ischemia (CLTI) is increasing year by year with the aging population, and the life quality and life expectancy of patients are severely affected. Effective revascularization is an essential treatment for symptomatic relief and ulcer healing in patients with CLTI, but the rate of restenosis in diseased vessels remains high as well as the efficacy of reoperation is not as good as it should be. Therefore, the strategy of the first treatment for CLTI is particularly important for its prognosis.However,the treatment for CLTI is still controversial, especially in terms of the timing of intervention, strategy of intervention, and means of intervention. This article briefly describes the current strategies of revascularization in chronic limb-threatening ischemia and its clinical controversies.
Abstract
The prevalence of chronic limb-threatening ischemia (CLTI) is increasing year by year with the aging population, and the life quality and life expectancy of patients are severely affected. Effective revascularization is an essential treatment for symptomatic relief and ulcer healing in patients with CLTI, but the rate of restenosis in diseased vessels remains high as well as the efficacy of reoperation is not as good as it should be. Therefore, the strategy of the first treatment for CLTI is particularly important for its prognosis.However,the treatment for CLTI is still controversial, especially in terms of the timing of intervention, strategy of intervention, and means of intervention. This article briefly describes the current strategies of revascularization in chronic limb-threatening ischemia and its clinical controversies.
关键词
慢性肢体威胁性缺血/血管腔内重建/动脉旁路手术
Key words
Chronic limb-threatening ischemia/Endovascular revascularization/Arterial bypass surgery