首页|甘油三酯葡萄糖乘积指数与消化性溃疡出血的相关性分析

甘油三酯葡萄糖乘积指数与消化性溃疡出血的相关性分析

扫码查看
目的 探究三酰甘油葡萄糖乘积指数(TyG)与消化性溃疡并发上消化道出血的关系.方法 选取 217 例消化性溃疡患者作为研究对象,分为出血组(观察组)及非出血组(对照组),分析两组患者年龄、性别、体重指数(BMI)、幽门螺杆菌(Hp)感染、血清血糖(Glu)、甘油三酯(TG)、血红蛋白、红细胞计数、血小板等指标与消化道出血的相关性.结果 观察组年龄、TyG指数、Hp感染均高于对照组,差异有统计学意义(P<0.05),观察组血红蛋白、红细胞比容均低于对照组,差异有统计学意义(P<0.05),两组间性别、BMI、吸烟、心率、血小板计数、高血压、糖尿病差异均无统计学意义(P>0.05).ROC曲线分析结果显示TyG指数、Hp感染、血红蛋白、红细胞比容预测消化性溃疡并发上消化道出血的曲线下面积分别为 0.708(95%CI 0.639~0.777)、0.641(95%CI 0.568~0.715)、0.099(95%CI 0.056~0.142)、0.083(95%CI 0.045~0.121).结论 TyG指数是消化性溃疡患者并发上消化道出血的危险因素,观察TyG指数对预测消化性溃疡患者病情发展可起到一定的作用.
Correlation analysis of triglyceride-glucose index and peptic ulcer bleeding
Objective To investigate the correlation between triglyceride-glucose index and upper gastrointestinal bleeding complicated by peptic ulcer.Methods A total of 217 patients with peptic ulcer were selected as the study subjects and these subjects were divided into bleeding group(observation group)and non-bleeding group(control group).The correlation between age,gender,body mass index(BMI),Helicobacter pylori(Hp)infection,serum blood glucose(Glu),triglyceride(TG),hemoglobin,red blood cell count,platelet and other indicators of patients in the two groups and gastrointestinal bleeding was analyzed respectively.Results The age,TyG index and Hp infection of the observation group were higher than those of the control group(all P<0.05);the hemoglobin and hematocrit value of the observation group were lower than those of the control group(both P<0.05).There were no significant differences in gender,BMI,smoking,heart rate,platelet count,hypertension and diabetes between the two groups(all P>0.05).The ROC curve showed that the area under the curve(AUC)of TyG index,Hp infection,hemoglobin and hematocrit value in predicting peptic ulcer bleeding were 0.708(95%CI:0.639-0.777),0.641(95%CI:0.568-0.715),0.099(95%CI:0.056-0.142)and 0.083(95%CI:0.045-0.121).Conclusion TyG index is a risk factor for peptic ulcer patients complicated with upper gastrointestinal bleeding,and observation of TyG index can play a certain role in predicting the development of peptic ulcer patients.

Peptic ulcerUpper gastrointestinal bleedingTriglyceride-glucose indexROC curve

马燕芳、高修银、李平静、李雷

展开 >

221006 江苏省,徐州医科大学附属医院全科医学科

221004 江苏省,徐州医科大学公共卫生学院

消化性溃疡 上消化道出血 三酰甘油葡萄糖乘积指数 ROC曲线

2024

中华消化病与影像杂志(电子版)
中华医学会

中华消化病与影像杂志(电子版)

CSTPCD
影响因子:0.641
ISSN:2095-2015
年,卷(期):2024.14(2)
  • 21