Research progress of Helicobacter pylori negative gastric mucosa-associated lymphoid tissue lymphoma
With the development of medical technology,more and more evidence shows that the occurrence of gastric mucosa-associated lymphoid tissue(MALT)lymphoma is closely related to the infection of Helicobacter pylori(Hp).Treatment by simple eradication of Hp has become the first-line treatment for the disease.However,it has been found that most patients with gastric MALT lymphoma do not have Hp infection,and the pathogenesis,endoscopic clinical manifestations and treatment methods of HP-negative gastric MALT lymphoma are different from those of positive patients.And treatment options are controversial.In this paper,the pathogenesis,clinical manifestations and treatment of HP-negative gastric MALT lymphoma are summarized,and the future treatment is prospected,so as to provide reference for improving the cure rate of this disease and reducing the incidence of adverse reactions.
Gastric mucosa-associated lymphoid tissue lymphomaHelicobacter pyloriPathogenesisDiagnosis and treatmentPrognosis