Research progress on anti-inflammatory and anti-fibrotic therapy for chronic pancreatitis
Chronic pancreatitis(CP)is characterized by chronic inflammation and fibrosis of the pancreas,with pancreatic acinar cell injury,stellate cell activation,and inflammatory cell infiltration collectively influencing the disease process.For a long time,the treatment of CP has focused on controlling symptoms and preventing complications,with no effective drugs available for intervening in the disease progression clinically.Therefore,the search for molecular targets and drugs that could be intervened is an important direction in CP research.This article reviews the pathogenesis of CP and the progress in anti-inflammatory and anti-fibrotic treatment research,aiming to provide more treatment options for CP.
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