Changes of blood lipid,blood glucose,protein and uric acid in patients with acute viral hepatitis and their correlation with prognosis
Objective To analyze the changes of blood lipid,blood glucose,protein and uric acid in patients with acute viral hepatitis and their correlation with prognosis.Methods A total of 100 patients with acute viral hepatitis admitted to the Affiliated Xuzhou Municipal Hospital ofXuzhou Medical University from January 2020 to January 2023 were included in the experimental group,and 60 healthy people in the same period were selected and included in the control group.The differences of blood lipid,blood glucose,protein,uric acid and prothrombin activity(PTA)between the experimental group and the control group were compared.According to the prognosis of the experimental group after 8 weeks of treatment,the patients were divided into good prognosis group and poor prognosis group respectively.The differences of the above indexes between the two groups were compared,and the correlation between the above indexes and the liver function and prognosis of the patients was summarized.Results Alanine aminotransferase(ALT),glutamic oxaloacetic transaminase(AST),total bilirubin(TBIL),triglyceride(TG),fasting blood-glucose(FPG),total protein(TP)and uric acid in the experimental group were higher than those in the control group,while total cholesterol(TC),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C),prealbumin(PA)and albumin(ALB)were lower than those in the control group(P＜0.05).Among 100 patients in the experimental group,71 cases reached the cure standard,and 21 cases had poor prognosis.ALT,AST,TBIL,TG,FPG,TP and uric acid in the good prognosis group were lower than those in the control group,while TC,HDL-C,LDL-C,ALB,PA and PTA were higher than those in the control group(P＜0.05).Conclusion The prognosis of some patients with acute viral hepatitis is not ideal,which is related to the remarkable abnormality of blood lipid,blood glucose,protein and uric acid at admission,and the aggravation of the above indexes is often accompanied by the remarkable damage of liver function.
万方数据
维普
