目的 了解2014年至2023年家族性渗出性玻璃体视网膜病变(FEVR)领域的研究热点和未来发展趋势。方法 以美国科学情报研究所Web of Science核心数据集SSCI、SCI-Expanded为数据源，检索FEVR相关文献。采用文献计量学分析软件CiteSpace6。2。R3对国家或地区、机构、作者、文献共被引和关键词进行分析。结果 共纳入316篇FEVR相关文献。该领域2014年至2023年年发文量整体呈波动上升趋势，其中2022年发文量最多，为51篇(16。14％，51/316);2015年发文量最小，为15篇(4。75％，15/316)。中国发文量最多，为137篇(43。35％，137/316);机构发文量中，上海交通大学位列第1位，为43篇;作者发文量中，上海交通大学附属新华医院赵培泉教授最多，为34篇。中介中心性最高的国家或地区为美国，0。91;机构为中国医学科学院，0。16;作者为丁小燕，0。12。316篇文献共聚类成4个领域，分别为#0 clinical characteristics(临床特点)、#1 ndp(NDP 基因)、#2 norrie disease(Norrie 病)、#3 retinopathy of prematurity(早产儿视网膜病变)。Chinese patients(中国患者)、tspan12(TSPAN12 基因)、variants(变异)、spectrum(谱)截止2023年仍为高频次关键词。结论 2014年至2023年FEVR研究文献呈增长趋势，其中中国研究机构和学者发文量最多;致病基因型和临床表型研究仍是未来重要发展方向。
Bibliometric analysis of research hotspots and trends in familial exudative vitreoretinopathy from 2014 to 2023
Objective To understand research hotspots and future development trends in the field of familial exudative vitreoretinopathy(FEVR)from 2014 to 2023.Methods Relevant literature on FEVR was retrieved using the Web of Science Core Collection(SSCI and SCI-Expanded)from the Institute for Scientific Information.The bibliometric analysis software CiteSpace 6.2.R3 was used to analyze countries or regions,institutions,authors,co-cited references,and keywords.Results A total of 316 FEVR-related articles were included.The annual number of publications in this field showed a fluctuating upward trend from 2014 to 2023,with the highest number of publications in 2022,51 papers(16.14％,51/316);and the lowest in 2015,15 papers(4.75％,15/316).China had the highest number of publications,with 137 papers(43.35％,137/316).Among institutions,Shanghai Jiao Tong University ranked first with 43 papers,while Professor Zhao Peiquan from Xinhua Hospital of Shanghai Jiao Tong University,had the highest number of publications among authors,with 34 papers.The country with the highest betweenness centrality was the United States,0.91;the institution was the Chinese Academy of Medical Sciences,0.16;and the author was Ding Xiaoyan,0.12.The 316 papers were clustered into four research areas:#0 clinical characteristics,#1 ndp,#2 norrie disease,and #3 retinopathy of prematurity.Keywords such as"Chinese patients,""TSPAN12,""variants,"and"spectrum"remained highly frequent up to 2023.Conclusions The number of publications on FEVR research from 2014 to 2023 show a growth trend,with Chinese research institutions and scholars contributing the most.Research on pathogenic genotypes and clinical phenotypes remains a crucial direction for future development.
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