Objective This study aimed to assess the awareness of trainees in physician standardized training towards the conse-quences of scientific misconduct and identify the main influencing factors,additionally,to provide targeted suggestions.Methods A questionnaire survey was conducted among 6 200 trainees from 17 National standardized training bases for residencies in Guangxi.The cognitive status of the consequences of scientific misconduct were analyzed and factors affecting trainees'cognition were examined in terms of grade,education level,research experience,publication experience,research integrity training experience,and research integ-rity knowledge level.Results The findings indicated that the awareness of trainees towards the consequences of scientific misconduct requires improvement.Notably,trainees from the 2020 and 2021 grade cohorts,with a master's degree or above,having led research projects,having participated in research integrity training,and with a high level of research integrity knowledge scored higher on the cognitive assessment of the impact of research misconduct.Conclusions Training bases should prioritize the education of research in-tegrity among trainees,enhance their identification with scientific research integrity,raise their awareness of the seriousness of the con-sequences of scientific misconduct,and uphold the belief of adhering to the bottom line of academic ethics.