Objective This study aims to provide medical scientific research support to further improve China's response to public health emergencies similar to the new coronavirus,and help consolidate national security and the development of peo-ple's health.Methods Combined with years of work experience and joint research with colleagues,the author analyzed the problems of expanding the application of large-scale compassionate drug use clinical trials in China from the perspective of ethi-cal management,and puts forward reasonable and feasible suggestions.Results There were many problems in the ethical man-agement of large-scale compassionate drug use in our country,but it was possible to solve them through the optimization of management mechanism.Conclusions We must respond to the next round of public health emergencies with a sense of urgency and responsibility,and continuously optimize the management mechanism of mass compassionate drug use,so that it can be-come a strong cornerstone for building national security and people's health.
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