Analysis of the Value of hs-CRP,NT-proBNP and NAR Indexes in the Di-agnosis of ACS Patients
Objective To investigate the value of hypersensitive C reactive protein(hs-CRP),N-terminal pro-B type natriuretic peptide(NT-proBNP)and neutrophil to albumin ratio(NAR)indexes in the diagnosis of ACS patients.Methods In total,71 ACS patients admitted from June 2020 to September 2022 were selected,and 56 healthy people undergoing physical examination during the same period were enrolled as the control group.According to different types of disease and numbers of vascular lesions,the research group was divided into three subgroups:ST segment elevation myocardial infarction(STEMI)sub-group,NSTEMI subgroup,unstable angina pectoris(UAP)subgroup,as well as single vascular lesion subgroup,double vascu-lar lesion subgroup,and multi-vascular lesion subgroup.hs-CRP,NT-proBNP,and NAR were compared between the research group and the control group,between subgroups with different types of disease,and between subgroups with different numbers of vascular lesions.The value of hs-CRP,NT-proBNP,and NAR alone or in combination for the diagnosis of ACS was explored.Results The levels of hs-CRP,NT-proBNP,and NAR in the research group were higher than those in the control group(P<0.05).The levels of hs-CRP,NT-proBNP,and NAR gradually decreased in the STEMI,NSTEMI,and UAP subgroups,which gradually increased in single vascular lesion subgroup,double vascular lesion subgroup,and multi-vascular lesion subgroup(P<0.05).The receiver operating characteristic(ROC)curve results showed that the area under the ROC curve(AUC)of hs-CRP,NT-proBNP,and NAR alone and in combination in diagnosing AIS was 0.820,0.815,0.883,and 0.914,respective-ly,and the AUC of the three indicators in combination was higher than that of single indicator alone(P<0.05,P<0.01).Conclusion The combined detection of hs-CRP,NT-proBNP and NAR has greater value in the diagnosis of ACS.
Acute coronary syndromeTypes of diseaseNumber of vascular lesionsHypersensitive C reactive pro-teinAmino-terminal brain natriuretic peptide precursorNeutrophil to albumin ratioDiagnosis
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