首页|外泌体miRNA在胃癌诊断及治疗中的研究进展

外泌体miRNA在胃癌诊断及治疗中的研究进展

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外泌体携带多种物质,包括蛋白质、脂质、微小RNA(miRNA)、环状RNA和长链非编码RNA.miRNA是一种内源性非编码RNA分子,在细胞中发挥重要的调控作用.目前越来越多的研究发现,胃癌细胞来源的外泌体miRNA广泛参与了胃癌的发生发展,早期检测外泌体miRNA对胃癌的诊断和治疗具有重要意义.本文对外泌体miRNA在胃癌诊断和治疗中的潜在作用研究进展进行综述.
Research Progress in Exosomal miRNA in the Diagnosis and Treatment of Gastric Cancer
Exosomes can carry various substances,including proteins,lipids,microRNAs(miRNA),circRNA,and long non-coding RNA(lncRNA).miRNA is an endogenous non-coding RNA molecule that plays an important regulatory role in cells.Currently,an increasing number of studies have found that exosome miRNA derived from gastric cancer cells are widely involved in the occurrence and development of gastric cancer,and that early detection of exosomes is of great signifi-cance for the diagnosis and treatment of gastric cancer.This article reviews the potential role of exosome miRNA in the diagno-sis and treatment of gastric cancer.

Stomach neoplasmsExosomesmiRNADiagnosisScreeningTreatmentReview

李彦杰、于建平、王虹宇、王进宝、杨高升、韩晓鹏

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730000 兰州,甘肃中医药大学第一临床医学院

730070 兰州,甘肃省中心医院普外科

胃肿瘤 外泌体 miRNA 诊断 筛查 治疗 综述

甘肃省自然科学基金项目兰州市科技计划项目

23JRRA13862023-4-65

2024

转化医学杂志
海军总医院

转化医学杂志

CSTPCD
影响因子:0.671
ISSN:2095-3097
年,卷(期):2024.13(2)
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