Application Value of Conventional Ultrasound Combined with Contrast-Enhanced Ultrasound in the Differential Diagnosis of Breast Intraductal Papilloma
Objective To investigate the value of conventional ultrasound combined with contrast-enhanced ultrasound ( CEUS ) in the differential diagnosis of intraductal papilloma ( IDP ) and breast cancer.Methods 53 breast IDP patients ( IDP group ) and 70 patients with breast cancer ( breast cancer group ) were selected from The First Hospital of Shanxi Medical University and Yuncheng Central Hospital from January 2020 to June 2023.Both groups received conventional ultrasound and CEUS,and the lesions were reclassified by combining the characteristics of conventional ultrasound and CEUS according to the Breast Imaging-Reporting and Data System ( BI-RADS ),namely the CEUS-BI-RADS grading method.The differences in CEUS imaging characteristics,BI-RADS,and CEUS-BI-RADS grading between the two groups were compared,and the differential diagnostic value of conventional ultrasound combined with CEUS for IDP and breast cancer was analyzed by receiver operating characteristic ( ROC ) curve.Results There were statistically significant differences in BI-RADS grading and CEUS-BI-RADS grading between the two groups ( P<0.05 ),and significant differences were found in the enhancement order,enhancement phase,posterior boundary,the proportion of enhancement range,and the proportion of crab foot between the IDP and breast cancer groups ( P<0.05 ) .The area under the curve ( AUC ) value of BI-RADS grading for the differential diagnosis of IDP and breast cancer was 0.783 ( 95％ CI:0.569～0.891 ),while the AUC value of CEUS-BI-RADS grading for the differential diagnosis of IDP and breast cancer was 0.914 ( 95％ CI:0.738～0.982 ) .There was a statistically significant difference in the diagnostic value between the two methods ( P<0.05 ) .Conclusion Conventional ultrasound combined with CEUS can improve the accuracy of the early differential diagnosis of IDP and breast cancer,guiding clinical treatment and improving patient prognosis and quality of life.
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