The Value of the Systemic Immunoinflammatory Index Combined with the Prognostic Nutritional Index in Assessing the Postoperative Prognosis of Patients with Acute Stanford Type A Aortic Dissection
Objective To investigate the value of the systemic immunoinflammatory index ( SII) combined with the prognostic nutritional index ( PNI ) in assessing the postoperative prognosis of patients with acute Stanford type A aortic dissec tion ( ATAAD ) .Methods 107 patients with ATAAD who underwent surgical treatment in Jiuquan People's Hospital from August 2020 to February 2024 were selected and divided into a death group ( 25 cases ) and a survival group ( 82 cases ) according to postoperative prognosis.SII and PNI were calculated.A multifactorial unconditional logistic regression model was established to determine the influencing factors,with ATAAD patients' postoperative prognosis as the dependent variable.Receiver operating characteristic ( ROC ) curves were plotted to evaluate the value of SII combined with PNI in assessing the postoperative prognosis of ATAAD patients.Results Compared with the survival group,the death group had higher SII and lower PNI,and the operation time,extracorporeal circulation time,and aortic cross-clamping time were prolonged ( P<0.05 ) .The independent risk factors for postoperative prognosis in patients with ATAAD were prolonged extracorporeal circulation time and elevated SII,while the independent protective factor was an elevated PNI ( P<0.05 ) .The area under the curve ( AUC ) for SII combined with PNI in assessing the postoperative prognosis of ATAAD patients was 0.880,which was greater than 0.794 and 0.790 assessed by SII and PNI alone ( P<0.05 ) .Conclusion Elevated SII and reduced PNI were associated with postoperative prognosis in ATAAD patients.The combination of SII and PNI was highly valuable in assessing the postoperative period of ATAAD patients.
Acute Stanford Type A Aortic DissectionSystemic Immunoinflammatory IndexPrognostic Nutritional IndexPostoperative PrognosisLogistic modelROC CurveArea under the curve