首页|全身免疫炎症指数联合预后营养指数对急性Stanford A型主动脉夹层患者术后预后的评估价值

全身免疫炎症指数联合预后营养指数对急性Stanford A型主动脉夹层患者术后预后的评估价值

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目的 研究全身免疫炎症指数(SII)联合预后营养指数(PNI)对急性Stanford A型主动脉夹层(ATAAD)患者术后预后的评估价值.方法 选取2020年8月至2024年2月在甘肃省酒泉市人民医院行手术治疗的ATAAD患者107例,根据术后预后分为死亡组(25例)和存活组(82例),计算SII、PNI.以ATAAD患者术后预后为因变量,建立多因素非条件Logistic回归模型确定其影响因素;绘制受试者工作特征(ROC)曲线评价SII联合PNI对ATAAD患者术后预后的评估价值.结果 与存活组比较,死亡组SII升高,PNI降低,手术时间、体外循环时间、主动脉阻断时间延长(P<0.05).ATAAD患者术后预后的独立危险因素为体外循环时间延长和SII升高,独立保护因素为PNI升高(P<0.05).SII联合PNI评估ATAAD患者术后预后的曲线下面积(AUC)为0.880,大于SII、PNI单独评估的0.794、0.790(P<0.05).结论 SII升高和PNI降低与ATAAD患者术后预后有关,SII联合PNI评估ATAAD患者术后的价值较高.
The Value of the Systemic Immunoinflammatory Index Combined with the Prognostic Nutritional Index in Assessing the Postoperative Prognosis of Patients with Acute Stanford Type A Aortic Dissection
Objective To investigate the value of the systemic immunoinflammatory index ( SII) combined with the prognostic nutritional index ( PNI ) in assessing the postoperative prognosis of patients with acute Stanford type A aortic dissec tion ( ATAAD ) .Methods 107 patients with ATAAD who underwent surgical treatment in Jiuquan People's Hospital from August 2020 to February 2024 were selected and divided into a death group ( 25 cases ) and a survival group ( 82 cases ) according to postoperative prognosis.SII and PNI were calculated.A multifactorial unconditional logistic regression model was established to determine the influencing factors,with ATAAD patients' postoperative prognosis as the dependent variable.Receiver operating characteristic ( ROC ) curves were plotted to evaluate the value of SII combined with PNI in assessing the postoperative prognosis of ATAAD patients.Results Compared with the survival group,the death group had higher SII and lower PNI,and the operation time,extracorporeal circulation time,and aortic cross-clamping time were prolonged ( P<0.05 ) .The independent risk factors for postoperative prognosis in patients with ATAAD were prolonged extracorporeal circulation time and elevated SII,while the independent protective factor was an elevated PNI ( P<0.05 ) .The area under the curve ( AUC ) for SII combined with PNI in assessing the postoperative prognosis of ATAAD patients was 0.880,which was greater than 0.794 and 0.790 assessed by SII and PNI alone ( P<0.05 ) .Conclusion Elevated SII and reduced PNI were associated with postoperative prognosis in ATAAD patients.The combination of SII and PNI was highly valuable in assessing the postoperative period of ATAAD patients.

Acute Stanford Type A Aortic DissectionSystemic Immunoinflammatory IndexPrognostic Nutritional IndexPostoperative PrognosisLogistic modelROC CurveArea under the curve

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735000 甘肃 酒泉,甘肃省酒泉市人民医院心胸外科

急性Stanford A型主动脉夹层 全身免疫炎症指数 预后营养指数 术后预后 Logistic模型 ROC曲线 曲线下面积

2024

转化医学杂志
海军总医院

转化医学杂志

CSTPCD
影响因子:0.671
ISSN:2095-3097
年,卷(期):2024.13(3)