首页|肠道菌群及其代谢产物与妊娠期糖尿病的关系研究进展

肠道菌群及其代谢产物与妊娠期糖尿病的关系研究进展

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近年全球妊娠期糖尿病(gestational diabetes mellitus,GDM)发病率逐年升高,肠道菌群紊乱、失调与机体代谢性疾病密切相关,而短链脂肪酸、氧化三甲胺、胆汁酸及酚类化合物等肠道菌群代谢物与饮食、胰岛素抵抗有关.因此本研究对GDM孕妇肠道菌群变化、肠道菌群及其代谢物在GDM发生、防治中的作用进行综述.
Research on the Relationship Between Intestinal Flora and Its Metabolites and Gestational Diabetes Mellitus
In recent years,the global incidence of gestational diabetes mellitus ( GDM ) has been increasing.Intestinal flora disorders are closely associated with metabolic diseases.Short-chain fatty acids,trimethylamine oxide,bile acids,and phenolic compounds,as metabolites of intestinal flora,are related to diet and insulin resistance.Therefore,this article reviewed the changes of intestinal flora in pregnant women with GDM and the role of intestinal flora and its metabolites in the occurrence,prevention,and treatment of GDM.

Gestational diabetes mellitusIntestinal floraMetaboliteInsulin resistanceReview

钟静、吴和明、张华、郑志远、蓝柳冰

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514031 广东 梅州,梅州市人民医院产科

514031 广东 梅州,梅州市人民医院产前诊断实验室

糖尿病,妊娠 肠道微生物组 代谢产物 综述

2024

转化医学杂志
海军总医院

转化医学杂志

CSTPCD
影响因子:0.671
ISSN:2095-3097
年,卷(期):2024.13(3)