首页|支气管镜术在新生儿呼吸困难伴气道异常中的应用

支气管镜术在新生儿呼吸困难伴气道异常中的应用

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目的 探讨支气管镜术在新生儿呼吸困难考虑气道异常时病因及治疗的临床应用意义.方法 回顾性选择2020年1月至2023年7月安徽省马鞍山市人民医院收治的不明原因呼吸困难患儿71例为研究对象,对其病例特点、镜检结果及治疗效果等进行总结分析.结果 71例不明原因呼吸困难新生儿行支气管镜检查,检查指征前3位分别为撤机失败、支气管肺发育不良(bronchopulmonary dysplasia,BPD)及喉鸣;镜检结果前4位病因为支气管内膜炎23例次(32.1%)、喉软骨软化15例次(21.1%)、气管-支气管软骨软化12例次(16.9%)、气管性支气管7例次(9.9%).18例无其他呼吸道并发症的支气管内膜炎患儿经支气管灌洗及对症支持治疗治愈,其余根据镜检结果予以对症治疗后症状较前缓解,支气管镜检查术中无严重并发症发生.结论 支气管镜术能够安全用于新生儿不明原因呼吸困难的诊断及治疗,当出现撤机失败、支气管肺发育不良及喉鸣时建议行支气管镜探查.
Application of Fiberoptic Bronchoscopy for Diagnosis and Treatment of Dyspnea Accompanied by Airway Abnormality in Neonates
Objective To investigate the clinical application significance of fiberoptic bronchoscopy (FB) in iden-tifying causes of neonatal dyspnea. Methods A total of 71 neonates with unexplained dyspnea admitted to the neonatal intensive care unit of Ma'anshan People's Hospital between January 2020 and July 2023 who underwent FB were retro-spectively analyzed. Their clinical characteristics,bronchoscopy results,and treatment effects were summarized and ana-lyzed. Results Among the 71 newborns with unexplained dyspnea who underwent bronchoscopy,the top three indications for bronchoscopy were failure of withdrawal from mechanical ventilation,bronchopulmonary dysplasia (BPD),and laryngeal wheezing. The top four diagnoses identified through bronchoscopy were endobronchitis (23 cases,32.1%),laryngeal chon-dromalacia (15 cases,21.1%),tracheobronchial chondromalacia (12 cases,16.9%),and tracheal bronchus (7 cases,9.9%). Eighteen children with endobronchial inflammation without other respiratory complications were cured by bronchial lavage and symptomatic supportive treatment,while symptoms of the remaining cases were relieved after treatment guided by bron-choscopy findings. No serious complications occurred during bronchoscopy. Conclusion Fiberoptic bronchoscopy can be safely used in the diagnosis and treatment of unexplained dyspnea in neonates. Bronchoscopy is recommended when with-drawal failure,bronchopulmonary dysplasia,or laryngeal wheezing occurs.

BronchoscopyDyspneaInfant,newborn

徐世进、郭佳琦、李丽

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243000 安徽 马鞍山,安徽省马鞍山市人民医院儿科

471000 河南 洛阳,河南省洛阳市妇幼保健院(河南省第二儿童医院) NICU

呼吸困难 支气管镜 婴儿,新生

2024

转化医学杂志
海军总医院

转化医学杂志

CSTPCD
影响因子:0.671
ISSN:2095-3097
年,卷(期):2024.13(4)